Liposomes are a revolutionary way of encapsulating active ingredients in a phospholipid “bubble” to protect and deliver them directly to the cells of your tissues, which are reached via the bloodstream.⑴

Liposomes are non-toxic, biocompatible, biodegradable, and have the following advantages as carriers in drug delivery: first, liposomes can reduce toxicity; second, hydrophilic and lipophilic agents can be incorporated into liposomes; third, liposomes control the drug release; and fourth, the liposome delivery system increases bioavailability. (2)

“Liposomes are valued for their biological and technological advantages, and are considered to be the most successful drug-carrier systems known to date.” – International Journal of Nanomedicine, Liposomes As Nanomedical Devices

Depending on the molecule, with Liposomes 90% of the ingredients can typically make it to the bloodstream.   Many common supplements  are digested by enzymes and bacteria in the stomach.  If they make it past the intestines to the liver, they are seen as a foriegn body and are mostly filtered out.   Studies show nearly all NAD+ boosters do not escape the liver at all, but are converted to NAM which is released into the bloodstream.   Liposomes protect ingredients from digestion. As they are composed of phospholipds that are very similar to the membrane of every cell in our body, they are seen as native and are not filtered out by the liver, which released them intact into the bloodstream where they dissolve after a few hours and release the payload where it can be taken up by cells.  

Liposomes protect ingredients through the GI tract, merging their contents into cells to improve the biodistribution of compounds.

Liposomes protect ingredients through the GI tract, merging their contents into cells to improve the biodistribution of compounds.

LIPOSOMES DEMONSTRATION

WHY LIPOSOMES

BIOAVAILABILITY ISSUES

LIPOSOMAL DELIVERY PROTECTS INGREDIENTS

Liposomes are a revolutionary way of encapsulating active ingredients in a phospholipid “bubble” to protect and deliver them directly to the cells of your tissues, which are reached via the bloodstream.⑴

“Liposomes are valued for their biological and technological advantages, and are considered to be the most successful drug-carrier systems known to date.”

International Journal of Nanomedicine

Depending on the molecule, with Liposomes 90% of the ingredients can typically make it to the bloodstream.   Many common supplements  are digested by enzymes and bacteria in the stomach.  If they make it past the intestines to the liver, they are seen as a foriegn body and are mostly filtered out.   Studies show nearly all NAD+ boosters do not escape the liver at all, but are converted to NAM which is released into the bloodstream.   Liposomes protect ingredients from digestion. As they are composed of phospholipds that are very similar to the membrane of every cell in our body, they are seen as native and are not filtered out by the liver, which released them intact into the bloodstream where they dissolve after a few hours and release the payload where it can be taken up by cells.  

Liposomes protect ingredients through the GI tract, merging their contents into cells to improve the biodistribution of compounds.

Liposomes protect ingredients through the GI tract, merging their contents into cells to improve the biodistribution of compounds.

LIPOSOMES DEMONSTRATION

WHY LIPOSOMES

BIOAVAILABILITY ISSUES

The aim of taking any supplement is to ensure its transport into the bloodstream. However, due to the low absorption and bioavailability rates of traditional oral capsules, active ingredients lose most of their potency while passing through the gastrointestinal tract or are simply not absorbed in the small intestine at all. The majority is excreted unused via the intestines or kidneys. ⑵

Liposomal delivery offers targeted and complete absorption of active ingredients with a delayed‑release effect, unlike all other nutrient delivery methods.

This increased circulation time of key nutrients in the bloodstream greatly improves bioavailability.

Ingredients are absorbed & utilized rather than being destroyed in the stomach.

The higher the bioavailability of an active substance, the more effect it has on the body. ⑶

This means greater efficacy & smaller doses needed to achieve better results.

IT SOLVES THE BIOAVAILABILITY PROBLEM

The aim of taking any supplement is to ensure its transport into the bloodstream. However, due to the low absorption and bioavailability rates of traditional oral capsules, active ingredients lose most of their potency while passing through the gastrointestinal tract or are simply not absorbed in the small intestine at all. The majority is excreted unused via the intestines or kidneys. ⑵

Liposomal delivery offers targeted and complete absorption of active ingredients with a delayed‑release effect, unlike all other nutrient delivery methods.

This increased circulation time of key nutrients in the bloodstream greatly improves bioavailability.

Ingredients are absorbed & utilized rather than being destroyed in the stomach.

The higher the bioavailability of an active substance, the more effect it has on the body. ⑶

This means greater efficacy & smaller doses needed to achieve better results.

A liposome is made up of a spherical vesicle with the inner contents containing the active ingredients, which are protected by an outer layer comprised of tiny fat-like particles, called the phospholipid layer.

HOW LIPOSOMES WORK

A liposome is made up of a spherical vesicle with the inner contents containing the active ingredients, which are protected by an outer layer comprised of tiny fat-like particles, called the phospholipid layer.

Liposomes are absorbed through the oral mucosal lining and through lymphatic mechanisms in the gut, bypassing first-pass metabolism and breakdown in the liver ensuring the retention of liposome integrity.

The phospholipids in the liposomes closely resemble the structure of your cell membranes, and as a result the body recognizes them as safe and friendly substances which are biocompatible.

Many nutraceutical supplements have been shown to cause problems in the liver at higher dosages. The risk of liver damage greatly limits the dosage that can safely be used, which diminishes the effectiveness. The liver does not filter out molecules delivered by liposomes, so the risk from toxicity is greatly diminished.

BIOCOMPATIBILITY & SAFETY

Liposomes are absorbed through the oral mucosal lining and through lymphatic mechanisms in the gut, bypassing first-pass metabolism and breakdown in the liver ensuring the retention of liposome integrity.

The phospholipids in the liposomes closely resemble the structure of your cell membranes, and as a result the body recognizes them as safe and friendly substances which are biocompatible.

Many nutraceutical supplements have been shown to cause problems in the liver at higher dosages. The risk of liver damage greatly limits the dosage that can safely be used, which diminishes the effectiveness. The liver does not filter out molecules delivered by liposomes, so the risk from toxicity is greatly diminished.

Liposomes were first discovered in 1965 and soon after were proposed as drug delivery systems. For the last five decades, advancements in this field have led to numerous clinical trials on liposomes for delivery of anti-fungal, antibiotic drugs, delivery of gene medicines, anesthetics and anti-inflammatory medications. This is an established technology, with a variety of types of liposomes being brought to market. (Source)

Liposomes were first discovered in 1965 and soon after were proposed as drug delivery systems.

For the last five decades, advancements in this field have led to numerous clinical trials on liposomes for delivery of anti-fungal, antibiotic drugs, delivery of gene medicines, anesthetics and anti-inflammatory medications.

This is an established technology, with a variety of types of liposomes being brought to market. (Source)

  • Protects against the harsh environment of the GI tract and increases oral uptake and absorption
  • Provides superior stability of active ingredients, designed for higher absorption and greater efficacy
  • Timing of the dose does not require accompaniment or exclusion of food as the absorption via the liposome avoids the digestive processes
  • Provides a larger nutrient payload per particle
  • The dose is slowly released so the supplement’s concentration level can stay fairly constant in the body

KEY ADVANTAGES OF LIPOSOMAL DELIVERY

  • Protects against the harsh environment of the GI tract and increases oral uptake and absorption
  • Provides superior stability of active ingredients, allowing for higher absorption and greater efficacy
  • Timing of the dose does not require accompaniment or exclusion of food as the absorption via the liposome avoids the digestive processes
  • Provides a larger nutrient payload per particle
  • The dose is slowly released so the supplement’s concentration level can stay fairly constant in the body

Our LIPO Caps™ powdered liposomes technology encapsulates nanosized particles in liposomes, which are then freeze-dried to remove the aqueous phase. It’s a bit like grapes that are dehydrated to raisins, except that liposomes re-inflate in the body. This ensures maximum bioavailability and stability, protecting the ingredients against degradation.

This encapsulation technology is clinically proven through safety, absorption and blood glucose studies to maximize nutrient bioavailability. ⑷

We use natural non-hydrogenated sunflower phosphatidylcholine in our manufacturing process, derived from non-GMO certified sunflower oil from Europe.

It undergoes a multi-step, purification and filtration process during liposome manufacturing to ensure the utmost purity.

OUR ENCAPSULATION PROCESS

Our LIPO Caps™ powdered liposomes technology encapsulates nanosized particles in liposomes, which are then freeze-dried to remove the aqueous phase. It’s a bit like grapes that are dehydrated to raisins, except that liposomes re-inflate in the body. This ensures maximum bioavailability and stability, protecting the ingredients against degradation.

This encapsulation technology is clinically proven through safety, absorption and blood glucose studies to maximize nutrient bioavailability. ⑷

We use natural non-hydrogenated sunflower phosphatidylcholine in our manufacturing process, derived from non-GMO certified sunflower oil from Europe.

It undergoes a multi-step, purification and filtration process during liposome manufacturing to ensure the utmost purity.